Basic Information
VIS ID
TVIS20003506
Fusion event
HPV-LOC107985856 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
20685607/20485846 (Hg38)
End
20685607/20485846 (Hg38)
Location type
Intronic
Target gene
LOC107985856
Nearest miRNA
hsa-mir-3125/Upstream/1137341; hsa-mir-10b/Downstream/4842794;
Nearest TSS
ENST00000437798/Upstream/34804; ENST00000272224/Downstream/15465;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/37619, chr2-CpG: 56/Downstream/165106
Upstream sequence
ttaataaCAGAATCTCTCCTTTGTACGAGAAATTCATTCTTTGTGGCTCAGGACTACCTGACCAGAACCAGTTCCTGTACCCTCCCCTTCAAGAAGGGGA
Downstream sequence
TGGGGTTGGGGGGTCATACAGCCTCTTGGGGAGGCCACTGTGAGATTTCTGACCAGAGTGAAACGAGGATCCTTCCAGCTAGAAAGCCTTGCATCCTGCG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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