Basic Information
VIS ID
TVIS20003562
Fusion event
HPV-LOC107986410 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr5
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
29041112/29041005 (Hg38)
End
29041112/29041005 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA5A
Target gene
LOC107986410
Nearest miRNA
hsa-mir-10397/Upstream/11885013; hsa-mir-103a-1/Downstream/2895097;
Nearest TSS
ENST00000502646/Upstream/231756; ENST00000602801/Downstream/102498;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/112475, chr5-CpG: 37/Downstream/2152840
Upstream sequence
ttccctctcttgtttacagctcagaaactgctgtaagcaaaaacaattgtagggctgacctcaccttttcccacttccacaggataacaattttgtgctg
Downstream sequence
TGTTCAATGTTCTTCAAATTAACTACTACATAACCCTTTCTGAATTCTACTGTATGAATTAATGAGGGCTTGGCCGTCAGTGTATAGACTATACCTTTAT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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