Fusion event
HPV-KCTD1 integration
Detection method
PCR and Sanger sequencing
Quality evaluation
Perfect
Integrated sequence
TACATAGGCCAGCATTAACCTCTAGGCGTACTGGCATTAGGTA
End
24130733/26550769 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1-2/Upstream/2229023; hsa-mir-122/Downstream/40698;
Upstream sequence
CTGGACACGTGCAGAAAGGCGGCTCGTTTCTCCGAGGCTGCGGTGAGCAGCTAAGTTAGTTGC
Junction sequence
CTGGACACGTGCAGAAAGGCGGCTCGTTTCTCCGAGGCTGCGGTGAGCAGCTAAGTTAGTTGCTTTACATAGGCCAGCATTAACCTCTAGGCGACTGGCATTAGG
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.