Basic Information
VIS ID
TVIS20003778
Fusion event
HPV-CSDE1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Perfect
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Start
2955
End
2981
Orient
+
Integrated sequence
AAAGCATTACAAGCAATTGAACTGCAA
Host Sequence
Chromosome
chr1
Cytoband
p13.2
Reference genome
End
115257404/114714783 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-101-1/Upstream/1832654; hsa-mir-1182/Downstream/1845241;
Upstream sequence
AGAAACGCAAAAAGCACTGGGCTGTAGACATAAAATTTATGTATTTTACTTATGTAAATTGCTCAATAAAT
Junction sequence
AGAAACGCAAAAAGCACTGGGCTGTAGACATAAAATTTATGTATTTTACTTATGTAAATTGCTCAATAAATGTTTAATGATAAAGCATTACAAGCAATTGAACTGC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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