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VISDB
Viral Integration Site DataBase
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TVIS20003780
Basic Information
VIS ID
TVIS20003780
Fusion event
HPV-GJD3 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Perfect
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Start
2482
End
2527
Orient
-
Integrated sequence
GGATGGAAATTTAGTTTCTATGGATGTAAAGCATAGACCATTGGTA
Host Sequence
Chromosome
chr17
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
38512014/40355762 (Hg38)
End
38512014/40355762 (Hg38)
Location type
Intronic
Target gene
GJD3
miRNAs that regulate target gene
hsa-mir-510-3p
;
hsa-mir-4474-3p
;
hsa-mir-4738-3p
;
hsa-mir-5582-3p
;
hsa-mir-548x-3p
;
hsa-mir-548j-3p
;
hsa-mir-548aq-3p
;
hsa-mir-548am-3p
;
hsa-mir-548aj-3p
;
hsa-mir-548ah-3p
;
hsa-mir-548ae-3p
;
hsa-mir-2681-5p
;
hsa-mir-411-5p
;
hsa-mir-6832-5p
;
hsa-mir-193b-5p
;
hsa-mir-6732-5p
;
hsa-mir-6856-5p
;
hsa-mir-7153-3p
;
hsa-mir-6758-5p
;
hsa-mir-7159-5p
;
hsa-mir-26b-3p
;
hsa-mir-3065-5p
;
hsa-mir-654-3p
;
hsa-mir-580-5p
;
hsa-mir-548f-3p
;
hsa-mir-548e-3p
;
hsa-mir-548az-3p
;
hsa-mir-548ar-3p
;
hsa-mir-548a-3p
;
hsa-mir-505-3p
;
hsa-mir-421
;
hsa-mir-524-5p
;
hsa-mir-520d-5p
;
hsa-mir-3182
;
hsa-mir-4680-3p
;
hsa-mir-5187-3p
;
hsa-mir-4427
;
hsa-mir-138-2-3p
;
hsa-mir-4762-5p
;
hsa-mir-6514-3p
;
hsa-mir-7977
;
hsa-mir-4633-5p
;
hsa-mir-6811-3p
;
hsa-mir-214-5p
;
hsa-mir-3065-3p
;
hsa-mir-532-5p
;
hsa-mir-6783-3p
;
hsa-mir-1343-3p
;
hsa-mir-4284
;
hsa-mir-6506-5p
;
hsa-mir-619-5p
;
hsa-mir-4772-3p
;
hsa-mir-4638-5p
;
hsa-mir-1307-3p
;
hsa-mir-6741-3p
;
hsa-mir-6852-5p
;
hsa-mir-6742-3p
;
hsa-mir-939-3p
;
hsa-mir-660-3p
;
hsa-mir-6890-3p
;
hsa-mir-3613-3p
;
hsa-mir-4668-5p
;
hsa-mir-629-3p
;
hsa-mir-3692-3p
;
hsa-mir-6867-3p
;
hsa-mir-4713-5p
;
hsa-mir-514b-5p
;
hsa-mir-513c-5p
;
hsa-mir-2355-5p
;
hsa-mir-4436b-5p
;
hsa-mir-6509-3p
;
hsa-mir-4755-3p
;
hsa-mir-942-5p
;
hsa-mir-6860
;
hsa-mir-612
;
hsa-mir-5189-5p
;
hsa-mir-3187-5p
;
hsa-mir-1285-3p
;
hsa-mir-1236-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-7113-3p
;
hsa-mir-4469
;
hsa-mir-372-5p
;
hsa-mir-371a-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-877-3p
;
hsa-mir-1273g-3p
;
hsa-mir-181a-2-3p
;
hsa-mir-6777-3p
;
hsa-mir-4639-3p
;
hsa-mir-382-3p
;
hsa-mir-605-5p
;
hsa-mir-24-3p
;
hsa-mir-1972
;
hsa-mir-34b-3p
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-383-3p
;
hsa-mir-4690-5p
;
hsa-mir-5196-5p
;
hsa-mir-4747-5p
;
hsa-mir-498
;
hsa-mir-6836-3p
;
hsa-mir-5001-3p
;
hsa-mir-4279
;
hsa-mir-23b-5p
;
hsa-mir-23a-5p
;
hsa-mir-6778-3p
;
hsa-mir-1976
;
hsa-mir-150-5p
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-6814-5p
;
hsa-mir-4714-3p
;
hsa-mir-5571-5p
;
hsa-mir-6829-3p
;
hsa-mir-6791-3p
;
hsa-mir-5009-3p
;
hsa-mir-512-3p
;
hsa-mir-552-3p
;
hsa-mir-4796-3p
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-4632-3p
Nearest miRNA
hsa-mir-1180/Upstream/162099; hsa-mir-10226/Downstream/1161402;
Nearest TSS
ENST00000595228/Upstream/4375;
ENST00000578774/Downstream/4893;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/10175
,
chr17-CpG: 150/Downstream/6951
Upstream sequence
GCTGGTGGCATGGGGCAAGTGGTCCCGAACTCCGGCTCCAGGGCCAGACTGCCGGCCTGGGCTAGACGCCAAGCCCTT
Junction sequence
GCTGGTGGCATGGGGCAAGTGGTCCCGAACTCCGGCTCCAGGGCCAGACTGCCGGCCTGGGCTAGACGCCAAGCCCTTATATGCCAATGGTCTATGCTTTACATCCATAGAAACTAAATTTCCATCCAATGCATTTCTTAAATTGTCATCTATGTAGTTCCAACGGGCACTGT
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Sample Information
×
Sample name
T3256
Sample type
Tumor
Gender
Female
CpG Island Information
×
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