Basic Information
VIS ID
TVIS20003787
Fusion event
HPV-FTMT integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Perfect
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Start
806
End
830
Orient
-
Integrated sequence
GTTAATGGGCACACTAGGAATTGTG
Host Sequence
Chromosome
chr5
Cytoband
q23.1
Reference genome
End
120789493/121453798 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10397/Upstream/2299082; hsa-mir-103a-1/Downstream/7643890;
Upstream sequence
TGGTTGTCTAACAAATCACATAAGAGTTTGTAGATATTTGCAATAAAAACTATGGGGAAG
Junction sequence
TGGTTGTCTAACAAATCACATAAGAGTTTGTAGATATTTGCAATAAAAACTATGGGGAAGGCTCTGGGTCTACTGCAAATTTAGC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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