VISDB Viral Integration Site DataBase

VIS ID

TVIS20003795

Fusion event

HPV-chr6 integration

Validated

Yes

Detection method

PCR and Sanger sequencing

Data source

Curated

Sample type

Disease

Squamous-cell carcinoma (SCC)

Quality evaluation

Perfect

Reported year

2015

PubMed ID

Virus name

HPV

Subtype

HPV16

Reference genome

Start

3506

End

3557

Orient

-

Integrated sequence

CCACACCACTAAGTTGTTGCACAGAGACTCAGTGGACAGTGCTCCAATCCTC

Chromosome

chr6

Cytoband

q23.3

Reference genome

Start

End

138286486/137965349 (Hg38)

Location type

Intronic

Target gene

PERP ; TNFAIP3

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-mir-29a-3p ; hsa-mir-125a-5p ; hsa-mir-125b-5p ; hsa-mir-215-5p ; hsa-mir-26b-5p ; hsa-mir-24-3p ; hsa-mir-629-5p ; hsa-mir-153-5p ; hsa-mir-374a-5p ; hsa-mir-136-5p ; hsa-mir-4709-3p ; hsa-mir-3185 ; hsa-mir-4635 ; hsa-mir-4729 ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-4670-3p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-5692a ; hsa-mir-141-5p ; hsa-mir-6811-5p ; hsa-mir-3915 ; hsa-mir-6511b-5p ; hsa-mir-4684-3p ; hsa-mir-6077 ; hsa-mir-4722-5p ; hsa-mir-1286 ; hsa-mir-873-5p ; hsa-mir-3928-3p ; hsa-mir-6873-5p ; hsa-mir-5586-3p ; hsa-mir-4642 ; hsa-mir-921 ; hsa-mir-3606-5p ; hsa-mir-335-3p ; hsa-mir-5096 ; hsa-mir-3658 ; hsa-mir-505-3p ; hsa-mir-3653-3p ; hsa-mir-5093 ; hsa-mir-3688-3p ; hsa-mir-580-5p ; hsa-mir-6507-5p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-23b-3p ; hsa-mir-23c ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-3679-3p ; hsa-mir-4777-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-6826-3p ; hsa-mir-520g-5p ; hsa-mir-4667-3p ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-586 ; hsa-mir-2278 ; hsa-mir-5700 ; hsa-mir-629-3p ; hsa-mir-374b-3p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-2116-3p ; hsa-mir-186-3p ; hsa-mir-1179 ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-19a-5p ; hsa-mir-18a-5p ; hsa-mir-29b-3p ; hsa-let-7a-5p ; hsa-let-7e-5p

Nearest miRNA

hsa-mir-10398/Upstream/2726093; hsa-mir-1202/Downstream/469864;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/97345, chr6-CpG: 65/Downstream/141702

Nearest cancer related gene

TNFAIP3(TSG, No orient, 0)

Upstream sequence

AGAGAGAAAGGGAGAAGAGAGAGGAAGGAAGGAAGGAAGGAAAGA

Junction sequence