Basic Information
VIS ID
TVIS20003810
Fusion event
HPV-VSTM2A integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Cell line
Disease
Not given
Quality evaluation
Perfect
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Start
560
End
597
Orient
-
Integrated sequence
CATGCATGGAGATACACCTACATTGCATGAATATATGT
Host Sequence
Chromosome
chr7
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
54144011/54076318 (Hg38)
End
54144011/54076318 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA7A
Target gene
VSTM2A
Nearest miRNA
hsa-mir-1183/Upstream/9194518; hsa-mir-10399/Downstream/2879467;
Nearest TSS
ENST00000635602/Upstream/128574; ENST00000629899/Downstream/124906;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/856819, chr7-CpG: 48/Downstream/465723
Upstream sequence
TATTTCAGTCACAGGATCAGGAATTTTATACTCACTCTAGCAATTATAGCACAAGCAGTAGC
Junction sequence
TATTTCAGTCACAGGATCAGGAATTTTATACTCACTCTAGCAATTATAGCACAAGCAGTAGCTTGTAATGGGCTCTGTCCGGTTCTGCTTGTCCAGCTGG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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