ANPEP _HNSC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20003849
Fusion event
HPV-ANPEP integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Head and neck squamous cell carcinoma (HNSCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
28928286
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Not given
Gene
E1
Start
835
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
90349829/89806598 (Hg38)
End
90349829/89806598 (Hg38)
Location type
Exon2
Target gene
ANPEP
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-30a-5p ; hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-24-3p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-10393/Upstream/438492; hsa-mir-1302-10/Downstream/44039;
Nearest TSS
ENST00000557528/Upstream/1226; ENST00000559419/Downstream/8264;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/29353, chr15-CpG: 90/Downstream/7572
Upstream sequence
tatttgccatccatatatcattcttggtgaggtgtctattgaggtctttggcccgttttttaatcgggtgtttttttcttgttgagggtttttttttttt
Downstream sequence
GCGGCTCAGGGAGCCTCAGGCCAGGCAGAGAACGGAGCAGCCCCAGGCCGGGCTTATATCCCCAAAGGGGAGGAGCCCCACAACAGGCAGACTGGGCAAA
Reference
Koneva, L. A., et al. HPV Integration in HNSCC Correlates with Survival Outcomes, Immune Response Signatures, and Candidate Drivers. Mol Cancer Res ,2018,16(1): 90-102.
Curate