Basic Information
VIS ID
TVIS20003879
Fusion event
HPV-chr15:q26.1 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Head and neck squamous cell carcinoma (HNSCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
28928286
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Not given
Gene
L1
Start
999
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
90359849/89816617 (Hg38)
End
90359849/89816617 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10393/Upstream/448511; hsa-mir-1302-10/Downstream/34020;
Nearest TSS
ENST00000557528/Upstream/1216; ENST00000559419/Downstream/21337;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/1276, chr15-CpG: 52/Downstream/77176
Nearby gene
ARPIN-AP3S2(+13981) ;
Upstream sequence
CCCTCAGGGCCACGTGGGAGAAGAATGGAGTGCCCCTTTGGCCTGGGAAGGAAGTAGGCAGAGCCCAGGTCTGGGGAATGACTTCTTACCTGCTGCAGCT
Downstream sequence
TCTGACTCTCTCCACTATCATATCTGGCATAATCTCCTCCATGTCTGACAAGCCAAGGAAAACACTACATCAGGCCAGGAGAGAATCTTCCCCCCGGAGC
Reference
Koneva, L. A., et al. HPV Integration in HNSCC Correlates with Survival Outcomes, Immune Response Signatures, and Candidate Drivers. Mol Cancer Res ,2018,16(1): 90-102.
Curate