EPSTI1 _HNSC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20003902
Fusion event
HPV-EPSTI1 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Head and neck squamous cell carcinoma (HNSCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
28928286
Virus Sequence
Virus name
HPV
Subtype
HPV33
Reference genome
Not given
Gene
L1
Start
3518
Host Sequence
Chromosome
chr13
Cytoband
q14.11
Reference genome
GRCh37/hg19
Start
43500467/42926331 (Hg38)
End
43500467/42926331 (Hg38)
Location type
Exon7
Target gene
EPSTI1
miRNAs that regulate target gene
hsa-mir-146a-5p ; hsa-mir-654-5p
Nearest miRNA
hsa-mir-2276/Upstream/1357936; hsa-mir-1267/Downstream/1269798;
Nearest TSS
ENST00000623511/Upstream/83444; ENST00000474320/Downstream/37252;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/653660, chr13-CpG: 38/Downstream/65607
Upstream sequence
ATCCAATACCAGGTGTTTTGACAAGTTAGCATCACCTGAATTTAAAACCTCTATGAACAATCTGCCTATAAAGGCACGAAGTTCTGAAAACATTAACTTA
Downstream sequence
CTATTGCTGATGCTCTCTAAATGCTTCTCTTCTAAGGTTTTCTTGAAGTCTTTTTTTCTCCTCCAGTTTATTGCTCTGAAATTGCAAATATCAAAACATA
Reference
Koneva, L. A., et al. HPV Integration in HNSCC Correlates with Survival Outcomes, Immune Response Signatures, and Candidate Drivers. Mol Cancer Res ,2018,16(1): 90-102.
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