GLTPD2 _HNSC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20003935
Fusion event
HPV-GLTPD2 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Head and neck squamous cell carcinoma (HNSCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
28928286
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Not given
Gene
E7
Start
820
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
4693069/4789774 (Hg38)
End
4693069/4789774 (Hg38)
Location type
Exon4
Target gene
GLTPD2
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1253/Upstream/2041592; hsa-mir-10226/Downstream/179928;
Nearest TSS
ENST00000595228/Upstream/815; ENST00000575079/Downstream/6370;
Nearest CpG islands
chr17-CpG: 173/Target, None/Upstream, None/Downstream
Upstream sequence
TTGGTGGTAGAAATTATGAGGGTTTTCAGCTTCTCATTCTTTTCTATTTCTTCCACACTTCTTTAATGATCATCTCTTACTTTCTTACTTTTCTTTCTAC
Downstream sequence
GGCTCCGTCTTCGCCTTCGCCACTAGGGAGGCCTTCACCAAGGTGACAGACCTGGAGGCTCGGGTGCACGGCCCGGACGCGGAGCACTACTGGTCGCTGG
Reference
Koneva, L. A., et al. HPV Integration in HNSCC Correlates with Survival Outcomes, Immune Response Signatures, and Candidate Drivers. Mol Cancer Res ,2018,16(1): 90-102.
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