Basic Information
VIS ID
TVIS20003981
Fusion event
HPV-EPHA5-AS1 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Disease
Head and neck squamous cell carcinoma (HNSCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Not given
Gene
E7
Start
669
Host Sequence
Chromosome
chr4
Cytoband
q13.1
Reference genome
End
66558821/65693103 (Hg38)
Location type
Exon4
Target gene
Nearest miRNA
hsa-mir-12113/Upstream/4770419; hsa-mir-1243/Downstream/583721;
Upstream sequence
CCACATTTTTTTACCCTTCAGTGACACTTCTGTCCATGTTATTGATATCACTGACAAATAAACTATCTGCTGCATGACTGGGGGATGAAGAATAAGGGTG
Downstream sequence
gccaggcatttttagtgatgtgtggcctcaccacttaaatccagtttattgaatctgaagtgatttgctcctctttctggactacacaataaacaccctc
Reference
Koneva, L. A., et al. HPV Integration in HNSCC Correlates with Survival Outcomes, Immune Response Signatures, and Candidate Drivers. Mol Cancer Res ,2018,16(1): 90-102.
Curate