Basic Information
VIS ID
TVIS20004013
Fusion event
HPV-chr13:q13.2 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Disease
Head and neck squamous cell carcinoma (HNSCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Not given
Gene
E7
Start
808
Host Sequence
Chromosome
chr13
Cytoband
q13.2
Reference genome
End
34789996/34215859 (Hg38)
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-2276/Upstream/10053355; hsa-mir-1267/Downstream/5448175;
Nearby gene
NBEA(-726427) ;
Upstream sequence
GTGACCTGCCTGCAAGCGTCTCAGGGTGGGATGGCAGTCATGGTGATGTACAGGCACTGCCCACTTGTCTCCAGCATGTGTACAGGCCTTGCCTTTCTTT
Downstream sequence
CCAGGTCTCCCTGAGTTATGCCTCAGCTCACTAAAGCAAAAACTTCACTTCTTTCTCCACCTGGGTAAGTTTTCAATGGCCCTGCACAGAAGTTTAAGTT
Reference
Koneva, L. A., et al. HPV Integration in HNSCC Correlates with Survival Outcomes, Immune Response Signatures, and Candidate Drivers. Mol Cancer Res ,2018,16(1): 90-102.
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