MUC16 _HNSC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004024
Fusion event
HPV-MUC16 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Head and neck squamous cell carcinoma (HNSCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
28928286
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Not given
Gene
E7
Start
333
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
9096240/8985564 (Hg38)
End
9096240/8985564 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
MUC16
Nearest miRNA
hsa-mir-1227/Upstream/596184; hsa-let-7e/Downstream/1052790;
Nearest TSS
ENST00000633603/Upstream/4222; ENST00000429566/Downstream/101497;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/153120, chr19-CpG: 18/Downstream/108006
Nearby gene
OR1M1(-107680) ;
Upstream sequence
CCCgtgtttgttttctatggccgccgtcaacaaatgacacagccttggtggctgaaacaacacaagtgattttcgtacagtcctggaggtcagaagtccc
Downstream sequence
GTTGATTTTTCTACCAGAGGGCTGCCTGTTGGCCATACTGAGGTTCCATGTGGGGATGACGAATTCTCCCCAGGCTCGTGAGTTCCTGTGAGGAGAAAAG
Reference
Koneva, L. A., et al. HPV Integration in HNSCC Correlates with Survival Outcomes, Immune Response Signatures, and Candidate Drivers. Mol Cancer Res ,2018,16(1): 90-102.
Curate