Basic Information
VIS ID
TVIS20004028
Fusion event
HPV-OR7E14P integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Head and neck squamous cell carcinoma (HNSCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
28928286
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Not given
Gene
E7
Start
747
Host Sequence
Chromosome
chr11
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
17073577/17052030 (Hg38)
End
17073577/17052030 (Hg38)
Location type
Exon1
Fragile sites / regions
FRA11C ; FRA11I
Target gene
OR7E14P
Nearest miRNA
hsa-mir-210/Upstream/1082409; hsa-let-7a-2/Downstream/1335757;
Nearest TSS
ENST00000527297/Upstream/37587; ENST00000620945/Downstream/23582;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/37173, chr11-CpG: 56/Downstream/25262
Upstream sequence
ggaatttgagcgtgacaatgactagtgtcagtaatgaagataaatcaatgatcaaagcatgatcagtgagtccaccctgaccaagaatgagtcgataaat
Downstream sequence
ttataaatggcagggaaaagaaaggccccctccttttatttatttatttatttatttattttttgttgagacatagtctcactctgtcgcccaggctgga
Reference
Koneva, L. A., et al. HPV Integration in HNSCC Correlates with Survival Outcomes, Immune Response Signatures, and Candidate Drivers. Mol Cancer Res ,2018,16(1): 90-102.
Curate