PLCXD2 _HNSC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004046
Fusion event
HPV-PLCXD2 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Disease
Head and neck squamous cell carcinoma (HNSCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV33
Reference genome
Not given
Gene
E6
Start
855
Host Sequence
Chromosome
chr3
Cytoband
q13.2
Reference genome
End
111416149/111697302 (Hg38)
Location type
Intron1
Target gene
Nearest miRNA
hsa-let-7g/Upstream/2094405; hsa-mir-12124/Downstream/415499;
Upstream sequence
TGGAGTGCGTGGGGGACCGGCTGTTGGCGGGTGAGGCTTGGCTTGAGGCACGCCTGGTGGAAAGGGGGAAAGAAACAGCGCCTCCCAGGGGCGGTGCCAC
Downstream sequence
TACCACATTATTGAGTGAGAATGTCTTCTAAGAAAGCAAAAAGCCTCTGAATAAAACAAGCACACTCGAGAGGCCTAAAAAGAAAAATTGGGTGATAAAG
Reference
Koneva, L. A., et al. HPV Integration in HNSCC Correlates with Survival Outcomes, Immune Response Signatures, and Candidate Drivers. Mol Cancer Res ,2018,16(1): 90-102.
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