hsa-mir-7-5p _HNSC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004049
Fusion event
HPV-THAP12 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Head and neck squamous cell carcinoma (HNSCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
28928286
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Not given
Gene
E7
Start
3452
Host Sequence
Chromosome
chr11
Cytoband
q13.5
Reference genome
GRCh37/hg19
Start
76091789/76380745 (Hg38)
End
76091789/76380745 (Hg38)
Location type
Exon1
Fragile sites / regions
FRA11H
Target gene
THAP12
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-7-5p ; hsa-mir-98-5p ; hsa-mir-24-3p
Nearest miRNA
hsa-mir-10392/Upstream/1045559; hsa-let-7a-2/Downstream/3021277;
Nearest TSS
ENST00000527297/Upstream/12102; ENST00000530460/Downstream/197;
Nearest CpG islands
chr11-CpG: 103/Target, None/Upstream, None/Downstream
Upstream sequence
gctctggctagttatctgcagcaggaacatgtccttaaggcacagatcactcatgctattgtttgtggttcaggaacgccttaagtggttttccgccctg
Downstream sequence
ggtgggccaggtgtttgttgccctcattctgggaagccaacaaccttcagcatgggcgtcatagccatcacgagcatgtcacagtgctgcagagattttg
Reference
Koneva, L. A., et al. HPV Integration in HNSCC Correlates with Survival Outcomes, Immune Response Signatures, and Candidate Drivers. Mol Cancer Res ,2018,16(1): 90-102.
Curate