VISDB Viral Integration Site DataBase

VIS ID

TVIS20004190

Fusion event

HPV-OR9Q1 integration

Validated

Yes

Detection method

APOT and sequencing

Data source

Curated

Sample type

Disease

Cervical carcinoma (CC)

Quality evaluation

Good

Reported year

2018

PubMed ID

Virus name

HPV

Subtype

HPV16

Reference genome

Strand

-

Gene

L2

Start

4178

End

4491

Orient

-

Integrated sequence

ATATATTTTTTTTTTGTTTGTTTGTTTGTTTTTTAATAAACTGTTATCACTTAACAATGCGACACAAACGTTCTGCAAAACGCACAAAACGTGCATCGGCTACCCAACTTTATAAAACATGCAAACAGGCAGGTACATGTCCACCTGACATTATACCTAAGGTTGAAGGCAAAACTATTGCTGATCAAATATTACAATATGGAAGTATGGGTGTATTTTTTGGTGGGTTAGGAATTGGAACAGGGTCGGGTACAG

Chromosome

chr11

Cytoband

q12.1

Reference genome

Start

End

57805208/58037736 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-876-3p ; hsa-mir-5087 ; hsa-mir-4765 ; hsa-mir-1236-5p ; hsa-mir-3613-3p ; hsa-mir-2355-3p ; hsa-mir-607 ; hsa-mir-676-3p ; hsa-mir-3671 ; hsa-mir-4775 ; hsa-mir-668-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-4762-5p ; hsa-mir-501-5p ; hsa-mir-500a-5p

Nearest miRNA

hsa-mir-129-2/Upstream/396396; hsa-let-7a-2/Downstream/1557341;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/284401, chr11-CpG: 132/Downstream/540464

Nearby gene

OR6Q1(-5776) ; OR9Q2(+152697) ;

Upstream sequence

AGTAGTTTCCTTGACTATATGCATTGAAAAGTATCTGTTTATAATGGAATTTACCCTCATAGCTACAAATACCTTTAAACCCAGAAGGACATTAGGCAGT

Downstream sequence

gagacggagtctcactcagtcgcccaggctgggatgcagtggcgcgatctcggctcactgcaagctctgccttctgggttcatgccattctcctgcctca

Target sequence

atatatattttttttttttttttttttttttttttttttttttttttttttttt