Basic Information
VIS ID
TVIS20004222
Fusion event
HPV-CCAT1 integration
Validated
No
Detection method
TaME-seq
Data source
Curated
Sample type
Cell line
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30679491
Virus Sequence
Virus name
HPV
Subtype
HPV18
Reference genome
Not given
Gene
L1
Start
5730
Host Sequence
Chromosome
chr8
Cytoband
q24.21
Reference genome
GRCh37.p10
Start
127218384/127218384 (Hg38)
End
127218384/127218384 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA8C ; FRA8E
Target gene
CCAT1
Nearest miRNA
hsa-mir-12123/Upstream/2396326; hsa-mir-10400/Downstream/577578;
Nearest TSS
ENST00000518652/Upstream/138510; ENST00000642795/Downstream/26253;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/659859, chr8-CpG: 29/Downstream/97258
Upstream sequence
GTAAAGATCTTTAGGACATGAGATATGAGTGTTTTAAAAAAATTTTTTTCTTTACAATTAGAAAAGGTCATAAAAATATACACAATGAAAAACATAAATT
Downstream sequence
TTATAACCAGACAAAAACTTTAATAATATTTGTCAAATGCCAAATCGGAGTCCAAAGCCATTGTCCATTTTAAGAAAatcatctgacttaacatcactac
Reference
Lagstrom, S., et al. TaME-seq: An efficient sequencing approach for characterisation of HPV genomic variability and chromosomal integration. Sci Rep ,2019,9(1): 524.
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