Fusion event
HPV-chr2:q24.1 integration
Detection method
WGS, RNA-seq, Whole-Exome sequencing, PCR
Disease
Head and neck squamous cell carcinoma (HNSCC)
Quality evaluation
Perfect
Integrated sequence
GTTCCAGGGTCTCCACAATATACAATTATTGCTGATGCAGGTGACTTTTATTTACATCCTAGTTATTACATGTTACGAAAACGACGTAAACGTTTACCAT| |ATTTTTTTTCAGATGTCTCTTTGGCTGCCTAGTGAGGCCACTGTCTACTTGCCTCCTGTCCCAGTATCTAAGGTTGTAAGCACGGATGAATATGTTGCAC
End
157166440/156309928 (Hg38)
Nearest miRNA
hsa-mir-128-1/Upstream/4941517; hsa-mir-10b/Downstream/2876907;
Junction sequence
AGGTGACTAATTAAATTCCCAAAGTGCTCCTAATATAAACACAAACTAGGCTGACCCTTCCCTTGAAAAC---TTTTTTTTCAGATGTCTCTTTGGCTGCCTAG
* Color:
Human Sequence
/
Virus Sequence
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Overlapped sequence
/
Unknown sequence
Parfenov, M., et al. Characterization of HPV and host genome interactions in primary head and neck cancers. Proc Natl Acad Sci U S A,2014,111(43): 15544-15549.