VISDB Viral Integration Site DataBase

VIS ID

TVIS20004272

Fusion event

HPV-ZBTB7C integration

Validated

Yes

Detection method

WGS, RNA-seq, Whole-Exome sequencing, PCR

Data source

Curated

Sample type

Disease

Head and neck squamous cell carcinoma (HNSCC)

Quality evaluation

Perfect

Reported year

2014

PubMed ID

Virus name

HPV

Subtype

HPV16

Reference genome

Gene

E1

Start

1565

Integrated sequence

GTAATGCAAAGGCAGCAATGTTAGCAAAATTTAAAGAGTTATACGGGGTGAGTTTTTCAGAATTAGTAAGACCATTTAAAAGTAATAAATCAACGTGTTG| |CGATTGGTGTATTGCTGCATTTGGACTTACACCCAGTATAGCTGACAGTATAAAAACACTATTACAACAATATTGTTTATATTTACACATTCAAAGTTTA

Chromosome

chr18

Cytoband

q21.1

Reference genome

Start

End

45664402/48138031 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-106b-3p ; hsa-mir-1228-3p ; hsa-mir-8485 ; hsa-mir-4650-5p ; hsa-mir-1972 ; hsa-mir-510-5p

Nearest miRNA

hsa-mir-1-2/Upstream/757466; hsa-mir-122/Downstream/532569;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/882, chr18-CpG: 58/Downstream/23395

Nearest cancer related gene

ZBTB7C(TSG, No orient, 0)

Junction sequence