hsa-mir-4745-3p _HNSC.png
hsa-mir-6842-5p _HNSC.png
hsa-mir-6739-3p _HNSC.png
hsa-mir-6744-3p _HNSC.png
hsa-mir-4524a-3p _HNSC.png
hsa-mir-7109-5p _HNSC.png
ARHGDIA _HNSC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004274
Fusion event
HPV-ARHGDIA integration
Validated
Yes
Detection method
WGS, RNA-seq, Whole-Exome sequencing, PCR
Data source
Curated
Sample type
Disease
Head and neck squamous cell carcinoma (HNSCC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Gene
E1
Start
1669
Integrated sequence
TGGTGTATTGCTGCATTTGGACTTACACCCAGTATAGCTGACAGTATAAAAACACTATTACAACAATATTGTTTATATTTACACATTCAAAGTTTAGCAT| |GTTCATGGGGAATGGTTGTGTTACTATTAGTAAGATATAAATGTGGAAAAAATAGAGAAACAATTGAAAAATTGCTGTCTAAACTATTATGTGTGTCTCC
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
End
79827395/81869519 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-151a-5p ; hsa-mir-877-3p ; hsa-mir-744-5p ; hsa-mir-423-5p ; hsa-mir-484 ; hsa-mir-183-5p ; hsa-mir-92a-3p ; hsa-mir-4745-3p ; hsa-mir-1538 ; hsa-mir-6894-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-891a-5p ; hsa-mir-4524a-3p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-361-3p ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-4768-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-4524b-3p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-151b ; hsa-mir-330-5p ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-4695-5p ; hsa-mir-6801-5p ; hsa-mir-298 ; hsa-mir-4783-3p ; hsa-mir-4729 ; hsa-mir-6510-5p ; hsa-mir-1273h-3p ; hsa-mir-6866-5p ; hsa-mir-877-5p ; hsa-mir-4653-3p ; hsa-mir-6847-3p ; hsa-mir-4771 ; hsa-mir-3166 ; hsa-mir-3975 ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-6768-5p ; hsa-mir-6743-5p ; hsa-mir-4688 ; hsa-mir-1236-5p ; hsa-mir-1275 ; hsa-mir-1293 ; hsa-mir-1343-3p ; hsa-mir-181a-3p ; hsa-mir-184 ; hsa-mir-1908-5p ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-mir-211-3p ; hsa-mir-221-5p ; hsa-mir-2467-5p ; hsa-mir-3064-5p ; hsa-mir-3188 ; hsa-mir-328-5p ; hsa-mir-3612 ; hsa-mir-3652 ; hsa-mir-3677-3p ; hsa-mir-375 ; hsa-mir-3912-5p ; hsa-mir-3937 ; hsa-mir-4265 ; hsa-mir-4283 ; hsa-mir-4296 ; hsa-mir-429 ; hsa-mir-4316 ; hsa-mir-4322 ; hsa-mir-4326 ; hsa-mir-4417 ; hsa-mir-4430 ; hsa-mir-4435 ; hsa-mir-4437 ; hsa-mir-4455 ; hsa-mir-4483 ; hsa-mir-4493 ; hsa-mir-4508 ; hsa-mir-4525 ; hsa-mir-4651 ; hsa-mir-4665-5p ; hsa-mir-4674 ; hsa-mir-4721 ; hsa-mir-4747-5p ; hsa-mir-4755-3p ; hsa-mir-4763-5p ; hsa-mir-4765 ; hsa-mir-4787-5p ; hsa-mir-5010-5p ; hsa-mir-5088-5p ; hsa-mir-5196-5p ; hsa-mir-5589-5p ; hsa-mir-608 ; hsa-mir-625-5p ; hsa-mir-635 ; hsa-mir-637 ; hsa-mir-6504-5p ; hsa-mir-650 ; hsa-mir-661 ; hsa-mir-663a ; hsa-mir-6739-3p ; hsa-mir-6747-5p ; hsa-mir-6751-5p ; hsa-mir-6752-5p ; hsa-mir-6761-5p ; hsa-mir-6774-5p ; hsa-mir-6783-3p ; hsa-mir-6787-5p ; hsa-mir-6795-5p ; hsa-mir-6803-5p ; hsa-mir-6842-3p ; hsa-mir-6842-5p ; hsa-mir-6852-5p ; hsa-mir-6885-5p ; hsa-mir-6887-5p ; hsa-mir-7109-5p ; hsa-mir-7110-5p ; hsa-mir-8068 ; hsa-mir-8073 ; hsa-mir-891a-3p ; hsa-mir-9500 ; hsa-mir-95-5p
Nearest miRNA
hsa-mir-10226/Upstream/175650; hsa-mir-4525/Downstream/367149;
Nearest CpG islands
chr17-CpG: 57/Target, None/Upstream, None/Downstream
Junction sequence
AACACAACCATTCCCCATGAAC---CCCCGCGGCCGCAGGGCACTCACCCGTCAGGTCCAGCTCCAGGGGGCCCGGGGCCGAGCTGCACACCAGGGTCAGGCCA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Parfenov, M., et al. Characterization of HPV and host genome interactions in primary head and neck cancers. Proc Natl Acad Sci U S A,2014,111(43): 15544-15549.
Curate