Fusion event
HPV-chr1:q31.2 integration
Detection method
WGS, RNA-seq, Whole-Exome sequencing, PCR
Disease
Head and neck squamous cell carcinoma (HNSCC)
Quality evaluation
Perfect
Integrated sequence
GGTGTTAGTGAAAGACACACTATATGCCAAACACCACTTACAAATATTTTAAATGTACTAAAAACTAGTAATGCAAAGGCAGCAATGTTAGCAAAATTTA| |AAGAGTTATACGGGGTGAGTTTTTCAGAATTAGTAAGACCATTTAAAAGTAATAAATCAACGTGTTGCGATTGGTGTATTGCTGCATTTGGACTTACACC
End
191331460/191362330 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/10923940; hsa-mir-1182/Downstream/1353998;
Junction sequence
TACTAATTCTGTAAAACTCACCCCGTATAACTCTT---[ACA]---TAAACAACAGTTTATAACAATTACAT---[AAACAACAG]---TAAAATGTTGTTTATGTAATTGTTATAA
* Color:
Human Sequence
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Virus Sequence
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Overlapped sequence
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Unknown sequence
Parfenov, M., et al. Characterization of HPV and host genome interactions in primary head and neck cancers. Proc Natl Acad Sci U S A,2014,111(43): 15544-15549.