Basic Information
VIS ID
TVIS20004432
Fusion event
HPV-FANCC integration
Validated
Yes
Detection method
APOT-PCR
Data source
Curated
Sample type
Disease
Oropharyngeal squamous cell carcinoma (OSCC)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chr9
Cytoband
q22.3
Reference genome
End
97869797/95107515 (Hg38)
Orient
-
Location type
Intron13
Target gene
Nearest miRNA
hsa-let-7a-1/Upstream/21421; hsa-mir-12126/Downstream/2256039;
Upstream sequence
GACATACTTCTAGGATTTATTTATTTGCTTTGAAACAACCCCCAGAAACGGGTAAGCACTGGCCCCTGAGAGAGGGAGCTAGGCAGCGGCCGAATTTACA
Downstream sequence
TTTTTTGTATAAAAGGAAACAGAGAAAAGTTCTCAACAGAATGTAGTCAGATTTTTATATTGTGGGAAAAAGAACAAAAGGCTCCTTGAAGACTCGCCTA
Target sequence
CTCGATTTCACACAAACCCAAATGGGCGGAATGGAAATTTCTTGACTTTCTTTCGTCTTGCTCACCAAGCAGTCAGGGCACCATGCCAGGAACTGACCT
Reference
Olthof, N. C., et al.Comprehensive analysis of HPV16 integration in OSCC reveals no significant impact of physical status on viral oncogene and virally disrupted human gene expression.2014, PLoS One 9(2): e88718.
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