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TVIS20004438
Basic Information
VIS ID
TVIS20004438
Fusion event
HPV-SLC7A1 integration
Validated
Yes
Detection method
APOT-PCR
Data source
Curated
Sample type
Tumor
Disease
Oropharyngeal squamous cell carcinoma (OSCC)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24586376
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.1
Host Sequence
Chromosome
chr13
Cytoband
q12
Reference genome
GRCh37.p5
Start
30135781/29561644 (Hg38)
End
30135781/29561644 (Hg38)
Orient
+
Location type
Exon1
Target gene
SLC7A1
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-mir-122-5p
;
hsa-mir-125b-5p
;
hsa-mir-652-3p
;
hsa-mir-155-5p
;
hsa-mir-124-3p
;
hsa-mir-24-3p
;
hsa-mir-671-5p
;
hsa-mir-328-3p
;
hsa-mir-92a-3p
;
hsa-mir-1260b
;
hsa-mir-3688-3p
;
hsa-mir-3978
;
hsa-mir-4694-3p
;
hsa-mir-4802-3p
;
hsa-mir-551b-5p
;
hsa-mir-3677-5p
;
hsa-mir-4435
;
hsa-mir-5693
;
hsa-mir-6739-3p
;
hsa-mir-375
;
hsa-mir-6858-5p
;
hsa-mir-4689
;
hsa-mir-1251-3p
;
hsa-mir-4784
;
hsa-mir-3194-5p
;
hsa-mir-3150b-3p
;
hsa-mir-4756-3p
;
hsa-mir-3919
;
hsa-mir-3916
;
hsa-mir-6876-5p
;
hsa-mir-4476
;
hsa-mir-5680
;
hsa-mir-651-3p
;
hsa-mir-3148
;
hsa-mir-7852-3p
;
hsa-mir-3668
;
hsa-mir-191-5p
;
hsa-mir-6079
;
hsa-mir-6828-5p
;
hsa-mir-5589-3p
;
hsa-mir-4786-3p
;
hsa-mir-4717-3p
;
hsa-mir-32-5p
;
hsa-mir-92b-3p
;
hsa-mir-26b-5p
;
hsa-mir-26a-5p
;
hsa-mir-181c-5p
;
hsa-mir-181d-5p
;
hsa-mir-181b-5p
;
hsa-mir-181a-5p
;
hsa-mir-1205
;
hsa-mir-1587
;
hsa-mir-185-3p
;
hsa-mir-2467-3p
;
hsa-mir-3158-5p
;
hsa-mir-3620-5p
;
hsa-mir-3665
;
hsa-mir-3678-3p
;
hsa-mir-4283
;
hsa-mir-4417
;
hsa-mir-4489
;
hsa-mir-4492
;
hsa-mir-4498
;
hsa-mir-4537
;
hsa-mir-4656
;
hsa-mir-4675
;
hsa-mir-4731-5p
;
hsa-mir-4741
;
hsa-mir-5001-5p
;
hsa-mir-541-3p
;
hsa-mir-654-5p
;
hsa-mir-657
;
hsa-mir-6756-5p
;
hsa-mir-6766-5p
;
hsa-mir-6804-5p
;
hsa-mir-6829-5p
;
hsa-mir-762
Nearest miRNA
hsa-mir-2276/Upstream/5399140; hsa-mir-1267/Downstream/10102390;
Nearest TSS
ENST00000623511/Upstream/42134;
ENST00000481738/Downstream/25148;
Nearest CpG islands
None/Target,
chr13-CpG: 551/Upstream/47009
,
chr13-CpG: 147/Downstream/33120
Upstream sequence
TCCTGTGGAACAGCCCAGGCAGCTCCCGAGGGGATATGTCGGGGGTGTCAGAGTGTTGTAAAAAGAGGGGGTTTCTAGTCTGAAAAGGCAAACTACAATT
Downstream sequence
GGAGAGTGATGGAGGACAGAAATCAAAACCTAATGTGCACAATAAAGACCTCAGCGTCCCTGGAACCACAAGGGCAGGCCCCAGGCATCACCGAAGAATC
Target sequence
AGTTTAATTTATCCTTTGACATAAATATTGTCTTGAAATTTCCATGAGTTTTTTGTTAAAAGCATTGGGCTAAGAGACTGAAATAACTTTTCTGTTCAA
Reference
Olthof, N. C., et al.Comprehensive analysis of HPV16 integration in OSCC reveals no significant impact of physical status on viral oncogene and virally disrupted human gene expression.2014, PLoS One 9(2): e88718.
Sample Information
×
Sample name
26
Sample type
Tumor
Gender
Male
CpG Island Information
×
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