Basic Information
VIS ID
TVIS20004438
Fusion event
HPV-SLC7A1 integration
Validated
Yes
Detection method
APOT-PCR
Data source
Curated
Sample type
Disease
Oropharyngeal squamous cell carcinoma (OSCC)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chr13
Cytoband
q12
Reference genome
End
30135781/29561644 (Hg38)
Orient
+
Location type
Exon1
Target gene
Nearest miRNA
hsa-mir-2276/Upstream/5399140; hsa-mir-1267/Downstream/10102390;
Upstream sequence
TCCTGTGGAACAGCCCAGGCAGCTCCCGAGGGGATATGTCGGGGGTGTCAGAGTGTTGTAAAAAGAGGGGGTTTCTAGTCTGAAAAGGCAAACTACAATT
Downstream sequence
GGAGAGTGATGGAGGACAGAAATCAAAACCTAATGTGCACAATAAAGACCTCAGCGTCCCTGGAACCACAAGGGCAGGCCCCAGGCATCACCGAAGAATC
Target sequence
AGTTTAATTTATCCTTTGACATAAATATTGTCTTGAAATTTCCATGAGTTTTTTGTTAAAAGCATTGGGCTAAGAGACTGAAATAACTTTTCTGTTCAA
Reference
Olthof, N. C., et al.Comprehensive analysis of HPV16 integration in OSCC reveals no significant impact of physical status on viral oncogene and virally disrupted human gene expression.2014, PLoS One 9(2): e88718.
Curate