hsa-mir-3190-5p _CESC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004484
Fusion event
HPV-ORC2 integration
Validated
Yes
Detection method
Multiplex RT-PCR, APOT assay
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2014
PubMed ID
23824673
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
K02718
Gene
E1/E2
Start
3010
Integrated sequence
ATGTGCTATTTATTACAAGGCCAGAGAAATGGGATTTAAACATATTAACCACCAAGTGGTGCCAACACTG GCTGTATCAAAGAATAAAGCATTACAAG| |CAATTGAACTGCAACTAACGTTAGAAACAATATATAACTCAC AATATAGTAATGAAAAGTGGACATTACAAGACGTTAGCCTTGAAGTGTATTTAACTG
Host Sequence
Chromosome
chr2
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
201823720/200958997 (Hg38)
End
201823720/200958997 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2I
Target gene
ORC2
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-877-5p ; hsa-mir-505-3p ; hsa-mir-100-5p ; hsa-mir-3190-5p ; hsa-mir-3926 ; hsa-mir-4786-5p ; hsa-mir-548s ; hsa-mir-6728-3p ; hsa-mir-6771-3p ; hsa-mir-6849-3p
Nearest miRNA
hsa-mir-10b/Upstream/11825886; hsa-mir-1244-1/Downstream/5824237;
Nearest TSS
ENST00000437798/Upstream/15838; ENST00000332935/Downstream/4261;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/94143, chr2-CpG: 53/Downstream/4295
Upstream sequence
ggggggggggggggggggggggggggggggggagggaggggggggtgagaggggggggggggggggggggggggggggggggggggggggggggggggga
Downstream sequence
AACTATTGACTGTGTCTCTCttttctttctttttttattgagacagggtctcactgtgttgctgcagcctcaaccacctgggctcaagcaatcctcccat
Reference
Lu, X., et al. Multiple-integrations of HPV16 genome and altered transcription of viral oncogenes and cellular genes are associated with the development of cervical cancer. PLoS One ,2014,9(7): e97588.
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