Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004487
Fusion event
HPV-PID1 integration
Validated
Yes
Detection method
Multiplex RT-PCR, APOT assay
Data source
Curated
Sample type
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Gene
E2
Start
3667
Integrated sequence
AGTTGTTGCACAGAGACTCAGTGGACAGTGCTCCAATCCTCACTGCATTTAAC AGCTCACACAAAGGACGGATTAACTGTAATAGTAACACTACACCCA| |TAGTACATTTAAAAGGTGATGCTA ATACTTTAAAATGTTTAAGATATAGATTTAAAAAGCATTGTACATTGTATACTGCAGTGTCGTCTACATG GCAT
Host Sequence
Chromosome
chr2
Cytoband
q36.3
Reference genome
End
230045578/229180862 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10b/Upstream/1708675; hsa-mir-1244-1/Downstream/2181846;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/999025, chr2-CpG: 50/Downstream/90130
Upstream sequence
ggggggggggggggggggggggggggggggggggggggggagggggggggggggggggggggggggggggggggggggggaggggggggggggggggggg
Downstream sequence
aacggcgctcgcccatctctcaggaccgactgacccgtgttcaactgctgtttcactggacgccgccagaacagcgacgctttccaaggcacgggcccct
Reference
Lu, X., et al. Multiple-integrations of HPV16 genome and altered transcription of viral oncogenes and cellular genes are associated with the development of cervical cancer. PLoS One ,2014,9(7): e97588.