hsa-mir-4799-5p _CESC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004496
Fusion event
HPV-C4orf17 integration
Validated
Yes
Detection method
Multiplex RT-PCR, APOT assay
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2014
PubMed ID
23824673
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
K02718
Gene
E1
Start
1841
Integrated sequence
AAATAGAGAAACAATTGAAAAATTGCTGTCTAA ACTATTATGTGTGTCTCCAATGTGTATGATGATAGAGCCTCCAAAATTGCGTAGTACAGCAGCAGC| |ATTA TATTGGTATAAAACAGGTATATCAAATATTAGTGAAGTGTATGGAGACACGCCAGAATGGATACAAAGAC AAACAGTATTACAACATAGTTTTA
Host Sequence
Chromosome
chr4
Cytoband
q23
Reference genome
GRCh37/hg19
Start
100450200/99529043 (Hg38)
End
100450200/99529043 (Hg38)
Location type
Intronic
Target gene
C4orf17
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-4799-5p ; hsa-mir-3613-3p ; hsa-mir-3163 ; hsa-mir-1252-3p ; hsa-mir-3646
Nearest miRNA
hsa-mir-12113/Upstream/531583; hsa-mir-1243/Downstream/1711752;
Nearest TSS
ENST00000502981/Upstream/9801; ENST00000504724/Downstream/28487;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/440065, chr4-CpG: 40/Downstream/34527
Upstream sequence
AGCAGGATCCCACGTAGATTATCTTAACAGAGTTTATCTCTTCAAATTATAGAATGCTGGATTGGGCTTCCTATGGCTGTGAAGTGCCATTGCTGGAGGT
Downstream sequence
CAAATATAATGTAGATTTATTTTTGCTAAACATAAAGTTAAATATTGTTTTATCAATTCCAATCATCAAAATCCCAGGTTGTTGGCTCATTTAGGCACTA
Reference
Lu, X., et al. Multiple-integrations of HPV16 genome and altered transcription of viral oncogenes and cellular genes are associated with the development of cervical cancer. PLoS One ,2014,9(7): e97588.
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