VISDB Viral Integration Site DataBase

VIS ID

TVIS20004500

Fusion event

HPV-SLC29A1 integration

Validated

Yes

Detection method

Multiplex RT-PCR, APOT assay

Data source

Curated

Sample type

Disease

Cervical carcinoma (CC)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HPV

Subtype

HPV16

Reference genome

Gene

E2

Start

2350

Integrated sequence

TTTATGTCATTTTTAACTGCA TTAAAAAGATTTTTGCAAGGCATACCTAAAAAAAATTGCATATTACTATATGGTGCAGCTAACACAGGTA AATCATT| |ATTTGGTATGAGTTTAATGAAATTTCTGCAAGGGTCTGTAATATGTTTTGTAAATTCTAAAAG CCATTTTTGGTTACAACCATTAGCAGATGCCAAAAT

Chromosome

chr6

Cytoband

p21.1

Reference genome

Start

End

44184762/44217025 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-16-5p ; hsa-mir-34b-5p ; hsa-mir-449c-5p ; hsa-mir-1277-5p ; hsa-mir-1910-3p ; hsa-mir-2682-5p ; hsa-mir-3714 ; hsa-mir-548an ; hsa-mir-6511a-5p ; hsa-mir-1185-1-3p ; hsa-mir-1185-2-3p ; hsa-mir-127-3p ; hsa-mir-7845-5p ; hsa-mir-328-5p ; hsa-mir-486-3p ; hsa-mir-6721-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-4722-5p ; hsa-mir-6133 ; hsa-mir-3166 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4419a ; hsa-mir-4510 ; hsa-mir-1827 ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4459 ; hsa-mir-4270 ; hsa-mir-1324 ; hsa-mir-6743-5p ; hsa-mir-4756-5p ; hsa-mir-4688 ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-4695-5p ; hsa-mir-4524b-3p ; hsa-mir-676-3p ; hsa-mir-202-5p ; hsa-mir-545-3p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-186-5p ; hsa-mir-548as-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-4743-3p ; hsa-mir-6888-3p ; hsa-mir-3671 ; hsa-mir-3688-5p ; hsa-mir-196a-3p ; hsa-mir-215-3p ; hsa-mir-6773-3p ; hsa-mir-1910-5p ; hsa-mir-4514 ; hsa-mir-4667-3p ; hsa-mir-4692 ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-940

Nearest miRNA

hsa-mir-10398/Upstream/782405; hsa-mir-10524/Downstream/37181;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/64193, chr6-CpG: 24/Downstream/2424

Upstream sequence

CCACGCCTccccgcccgccccgcgcgcccgctccccccgcAAACTTgccccgccaccccgcccagcggcggggcccggggcccggggcccgggACTCACC

Downstream sequence

TCAGGGTGGATCAGGAGCCCCAAAAGAAAAATTGAGAATTGCCTGGAGAAGAACTCCTGCTAGACTGAGGGAGAAGGGTTAGGGAACTCCAGGGGCATTG