Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004534
Fusion event
HPV-FHOD3 integration
Validated
Yes
Detection method
Multiplex RT-PCR, APOT assay
Data source
Curated
Sample type
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Gene
E1
Start
3337
Integrated sequence
GTGGTAGAGGGTCAAGTTGACTATTATG GTTTATATTATGTTCATGAAGGAATACGAACATATTTTGTGCAGTTTAAAGATGATGCAGAAAAATATAG | |TAAAAATAAAGTATGGGAAGTTCATGCGGGTGGTCAGGTAATATTATGTCCTACATCTGTGTTTAGCAGC AACGAAGTATCCTCTCCTGAAATTATTAG
Host Sequence
Chromosome
chr18
Cytoband
q12.2
Reference genome
Start
End
34242009/36662046 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1-2/Upstream/727904; hsa-mir-122/Downstream/995089;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/363365, chr18-CpG: 17/Downstream/83615
Upstream sequence
AGAGCCctctgccaggcttgatttctgaaagggagtgtgaaacagtgccttctgccaaactgcatggggtgtgaacccacagtaaaaagtaaacctttgt
Downstream sequence
AAAACTACAGGAATATTTGAACTATTTGTGTTCAAGTATTCAAATGAAACAAACAAGCAAACAACCACACCTCAAGCGCATATGTGGTTGTGAGGCTTTG
Reference
Lu, X., et al. Multiple-integrations of HPV16 genome and altered transcription of viral oncogenes and cellular genes are associated with the development of cervical cancer. PLoS One ,2014,9(7): e97588.