BRSK1 _CESC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004556
Fusion event
HPV-BRSK1 integration
Validated
Yes
Detection method
FISH, WGS, RNA-seq, qPCR
Data source
Curated
Sample type
Cell line
Disease
Cervical carcinoma (CC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
24201445
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Gene
E7
Start
582
End
607
Integrated sequence
TTGCATGAATATATGTTAGATTTGCA
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
GRCh37/hg19
Start
55821546/55310178 (Hg38)
End
55821576/55310208 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
BRSK1
miRNAs that regulate target gene
hsa-mir-339-5p ; hsa-mir-6825-5p ; hsa-mir-7106-5p ; hsa-mir-1538 ; hsa-mir-4745-3p ; hsa-mir-765 ; hsa-mir-6077 ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-1247-3p ; hsa-mir-6753-5p ; hsa-mir-4779 ; hsa-mir-129-5p ; hsa-mir-4632-3p
Nearest miRNA
hsa-let-7e/Upstream/64928; hsa-mir-10394/Downstream/77973;
Nearest TSS
ENST00000633603/Upstream/6130; ENST00000498738/Downstream/2287;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/5269, chr19-CpG: 27/Downstream/2739
Nearest cancer related gene
BRSK1(TSG, No orient, 0)
Upstream sequence
TTTTCGTACAGTCCTGGAGGTCAGAAGTCCC
Target sequence
tttcgtacagtcctggaggtcagaagtccc
Junction sequence
TTTTCGTACAGTCCTGGAGGTCAGAAGTCCCTGTATTGCATGAATATATGTTAGATTTGC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Akagi, K., et al.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res ,2014,24(2): 185-199.
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