Fusion event
HPV-chrX:q27.3 integration
Detection method
FISH, WGS, RNA-seq, qPCR
Disease
Cervical carcinoma (CC)
Quality evaluation
Perfect
Integrated sequence
AGGGGATGCTATATCAGATGACGAGA
End
144778324/145696806 (Hg38)
Nearest miRNA
hsa-let-7f-2/Upstream/4770547; hsa-mir-105-1/Downstream/295944;
Downstream sequence
GAGCTCAATTTGGAAGAAAAGAACCAGTG
Target sequence
AGCTCAATTTGGAAGAAAAGAACCAGTG
Junction sequence
CAGGGGATGCTATATCAGATGACGAGCTCAATTTGGAAGAAAAGAACCAGTG
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Akagi, K., et al.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res ,2014,24(2): 185-199.