Basic Information
VIS ID
TVIS20004558
Fusion event
HPV-chrX:q27.3 integration
Validated
Yes
Detection method
FISH, WGS, RNA-seq, qPCR
Data source
Curated
Sample type
Disease
Cervical carcinoma (CC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Gene
E1
Start
950
End
975
Integrated sequence
AGGGGATGCTATATCAGATGACGAGA
Host Sequence
Chromosome
chrX
Cytoband
q27.3
Reference genome
End
144778324/145696806 (Hg38)
Fragile sites / regions
Nearest miRNA
hsa-let-7f-2/Upstream/4770547; hsa-mir-105-1/Downstream/295944;
Downstream sequence
GAGCTCAATTTGGAAGAAAAGAACCAGTG
Target sequence
AGCTCAATTTGGAAGAAAAGAACCAGTG
Junction sequence
CAGGGGATGCTATATCAGATGACGAGCTCAATTTGGAAGAAAAGAACCAGTG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Akagi, K., et al.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res ,2014,24(2): 185-199.
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