BRSK1 _CESC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004571
Fusion event
HPV-BRSK1 integration
Validated
Yes
Detection method
FISH, WGS, RNA-seq, qPCR
Data source
Curated
Sample type
Disease
Cervical carcinoma (CC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Gene
E4
Start
3486
End
3513
Integrated sequence
CCAGACACCGGAAACCCCTGCCACACCA
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
End
55821587/55310219 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7e/Upstream/64944; hsa-mir-10394/Downstream/77962;
Nearest cancer related gene
BRSK1(TSG, No orient, 0)
Upstream sequence
GAGGTCAGAAGTCCCACATGGTCTCT
Target sequence
aggtcagaagtcccacatggtctct
Junction sequence
GAGGTCAGAAGTCCCACATGGTCTCTTGCCAGACACCGGAAACCCCTGCCACACC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Akagi, K., et al.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res ,2014,24(2): 185-199.
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