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Viral Integration Site DataBase
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TVIS20004573
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004573
Fusion event
HPV-RPA3 integration
Validated
Yes
Detection method
FISH, WGS, RNA-seq, qPCR
Data source
Curated
Sample type
Cell line
Disease
Cervical carcinoma (CC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
24201445
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Gene
L2
Start
4541
End
4578
Integrated sequence
CCTTCTATAGTTTCTTTAGTGGAAGAAACTAGTTTTAT
Host Sequence
Chromosome
chr7
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
7679158/7639527 (Hg38)
End
7679190/7639559 (Hg38)
Location type
Intronic
Target gene
RPA3
miRNAs that regulate target gene
hsa-mir-26b-5p
;
hsa-mir-615-3p
Nearest miRNA
hsa-mir-339/Upstream/572482; hsa-mir-10399/Downstream/10487661;
Nearest TSS
ENST00000635602/Upstream/1121;
ENST00000471760/Downstream/467;
Nearest CpG islands
None/Target,
chr7-CpG: 39/Upstream/72135
,
chr7-CpG: 69/Downstream/650
Upstream sequence
AAGGAGAACTGGTTGCTAGAATATCTGGGTCCT
Junction sequence
AAGGAGAACTGGTTGCTAGAATATCTGGGTCCTCCTTCTATAGTTTCTTTAGTGGAAGAAACTAGTTTTA
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Akagi, K., et al.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res ,2014,24(2): 185-199.
Sample Information
×
Sample name
Caski
Sample type
Cell line
Gender
Female
CpG Island Information
×
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