Basic Information
VIS ID
TVIS20004581
Fusion event
HPV-chr7:q11.21 integration
Validated
Yes
Detection method
FISH, WGS, RNA-seq, qPCR
Data source
Curated
Sample type
Cell line
Disease
Cervical carcinoma (CC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
24201445
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Gene
L2
Start
5597
End
5621
Integrated sequence
TTACGAAAACGACGTAAACGTTTAC
Host Sequence
Chromosome
chr7
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
62984329/63523951 (Hg38)
End
62984355/63523977 (Hg38)
Fragile sites / regions
FRA7J
Nearest miRNA
hsa-mir-1183/Upstream/6118861; hsa-mir-10399/Downstream/97113;
Nearest TSS
ENST00000635602/Upstream/129674; ENST00000450544/Downstream/369501;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/125503, chr7-CpG: 36/Downstream/32581
Downstream sequence
AGAGTCGGAGAGTGGCTGGGCACAGTG
Target sequence
gagtcggagaGTggctgggcacagtg
Junction sequence
GTTACGAAAACGACGTAAACGTTTAGAGTCGGAGAGTGGCTGGGCACAGTG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Akagi, K., et al.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res ,2014,24(2): 185-199.
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