BRSK1 _CESC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004584
Fusion event
HPV-BRSK1 integration
Validated
Yes
Detection method
FISH, WGS, RNA-seq, qPCR
Data source
Curated
Sample type
Disease
Cervical carcinoma (CC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Gene
L1
Start
6876
End
6902
Integrated sequence
CTAGAAGATACTTATAGGTTTGTAACC
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
End
55818824/55307456 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7e/Upstream/62151; hsa-mir-10394/Downstream/80725;
Nearest cancer related gene
BRSK1(TSG, No orient, 0)
Downstream sequence
AAGCCTCGCGTGGTGGTGGGCTCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAG
Target sequence
agcctcgcgtggtggtgggctcctgtaatcccagctactcaggaggctgaggcag
Junction sequence
ACTAGAAGATACTTATAGGTTTGTAACATCAAAGCCTCGCGTGGTGGTGGGCTCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Akagi, K., et al.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res ,2014,24(2): 185-199.
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