Basic Information
VIS ID
TVIS20004587
Fusion event
HPV-PRR30 integration
Validated
Yes
Detection method
FISH, WGS, RNA-seq, qPCR
Data source
Curated
Sample type
Cell line
Disease
Cervical carcinoma (CC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
24201445
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Region type
LCR
Start
7876
End
7901
Integrated sequence
TTTACAAGCAACTTATATAATAATAC
Host Sequence
Chromosome
chr2
Cytoband
p23.3
Reference genome
GRCh37/hg19
Start
27360017/27137149 (Hg38)
End
27360043/27137175 (Hg38)
Location type
Intronic
Target gene
PRR30
Nearest miRNA
hsa-mir-1301/Upstream/1808428; hsa-mir-10b/Downstream/859192;
Nearest TSS
ENST00000437798/Upstream/2474; ENST00000407815/Downstream/2228;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/2330, chr2-CpG: 19/Downstream/12970
Downstream sequence
CAAGGCCTGGGCTTCAGGGAGGTAGTG
Target sequence
AAGGCCTGGGCTTCAGGGAGGTAGTG
Junction sequence
ATTTACAAGCAACTTATATAATAATAAGCCAAGGCCTGGGCTTCAGGGAGGTAGTG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Akagi, K., et al.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res ,2014,24(2): 185-199.
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