hsa-mir-21-5p _CESC.png
TP63 _CESC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004598
Fusion event
HPV-TP63 integration
Validated
Yes
Detection method
FISH, WGS, RNA-seq, qPCR
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
24201445
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Gene
E2
Start
3719
End
3745
Integrated sequence
AGGACATAATGTAAAACATAAAAGTGC
Host Sequence
Chromosome
chr3
Cytoband
q28
Reference genome
GRCh37/hg19
Start
189612825/189895036 (Hg38)
End
189612849/189895060 (Hg38)
Location type
Intronic
Target gene
TP63
miRNAs that regulate target gene
hsa-mir-203a-3p ; hsa-mir-92a-3p ; hsa-mir-21-5p ; hsa-mir-124-3p ; hsa-mir-301b-3p ; hsa-mir-129-5p ; hsa-mir-6885-3p ; hsa-mir-4477b ; hsa-mir-1178-3p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-4428
Nearest miRNA
hsa-let-7g/Upstream/65027; hsa-mir-3137/Downstream/5239446;
Nearest TSS
ENST00000440867/Upstream/105235; ENST00000412203/Downstream/69061;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/947273, chr3-CpG: 99/Downstream/225231
Nearest cancer related gene
TP63(OG, No orient, 0)
Upstream sequence
GAGTGACGATGATGTACAGATTCTT
Target sequence
AGTGACGATGATGTACAGATTCTT
Junction sequence
GAGTGACGATGATGTACAGATTCTTCAGGAGTGACGATGATGTACAGATTCTTCAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Akagi, K., et al.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res ,2014,24(2): 185-199.
Curate