Basic Information
VIS ID
TVIS20004606
Fusion event
HPV-chr9:q22.33 integration
Validated
Yes
Detection method
FISH, WGS, RNA-seq, qPCR
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
24201445
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Gene
E7
Start
822
End
847
Integrated sequence
GGAATTGTGTGCCCCATCTGTTCTCA
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
100620041/97857759 (Hg38)
End
100620065/97857783 (Hg38)
Nearest miRNA
hsa-let-7a-1/Upstream/494078; hsa-mir-12126/Downstream/371366;
Nearest TSS
ENST00000422679/Upstream/4505; ENST00000473205/Downstream/54688;
Nearest CpG islands
chr9-CpG: 29/Target, None/Upstream, None/Downstream
Nearby gene
PTCSC2(-1044) ; LOC110121153(+4822) ;
Upstream sequence
GGCCTCCCACCGGCCGACGACACCA
Target sequence
GCCTCCCACCGGCCGACGACACCA
Junction sequence
GGCCTCCCACCGGCCGACGACACCAGGAATTGTGTGCCCCATCTGTTCTC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Akagi, K., et al.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res ,2014,24(2): 185-199.
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