Basic Information
VIS ID
TVIS20004613
Fusion event
HPV-LOC110121154 integration
Validated
Yes
Detection method
FISH, WGS, RNA-seq, qPCR
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
24201445
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Gene
E1
Start
1886
End
1916
Integrated sequence
AGACAAACAGTATTACAACATAGTTTTAATG
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
100638320/97876038 (Hg38)
End
100638345/97876063 (Hg38)
Location type
Intronic
Target gene
LOC110121154
Nearest miRNA
hsa-let-7a-1/Upstream/512357; hsa-mir-12126/Downstream/353086;
Nearest TSS
ENST00000422679/Upstream/22784; ENST00000473205/Downstream/36408;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/18128, chr9-CpG: 53/Downstream/46153
Target sequence
gcactgcaattgttgatgagctttg
Junction sequence
AAGACAAACAGTATTACAACATAGTTGTAATTCTGCCGAATTACAACTTTACACTGCAATTGCACTGCAATTGTTGATGAGCTTTG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Akagi, K., et al.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res ,2014,24(2): 185-199.
Curate