Basic Information
VIS ID
TVIS20004614
Fusion event
HPV-chr9:q22.33 integration
Validated
Yes
Detection method
FISH, WGS, RNA-seq, qPCR
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
24201445
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Gene
E1
Start
2006
End
2034
Integrated sequence
TTGGCAGACACTAATAGTAATGCAAGTGC
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
100712492/97950178 (Hg38)
End
100712460/97950210 (Hg38)
Nearest miRNA
hsa-let-7a-1/Upstream/586497; hsa-mir-12126/Downstream/278939;
Nearest TSS
ENST00000422679/Upstream/5322; ENST00000473205/Downstream/33151;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/27409, chr9-CpG: 276/Downstream/32490
Nearby gene
HEMGN(-5263) ;
Upstream sequence
ATTGGCAGACACTAATAGTAATGCAAGTG
Target sequence
ctcatgccatggttttcagttccatcaggtca
Junction sequence
ATTGGCAGACACTAATAGTAATGCAAGTGACCTGATGGAACTGAAAACCATGGCATGAGA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Akagi, K., et al.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res ,2014,24(2): 185-199.
Curate