hsa-mir-362-3p _CESC.png
HEMGN _CESC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004618
Fusion event
HPV-HEMGN integration
Validated
Yes
Detection method
FISH, WGS, RNA-seq, qPCR
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
24201445
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Gene
L2
Start
4353
End
4380
Integrated sequence
CTATTGCTGAACAAATATTACAATATGG
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
100691903/97929500 (Hg38)
End
100691782/97929621 (Hg38)
Location type
Intronic
Target gene
HEMGN
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-1287-3p ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485
Nearest miRNA
hsa-let-7a-1/Upstream/565819; hsa-mir-12126/Downstream/299528;
Nearest TSS
ENST00000422679/Upstream/6930; ENST00000473205/Downstream/8772;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/6731, chr9-CpG: 276/Downstream/53079
Upstream sequence
ATAAAAGCTGTAAAATATAATT
Target sequence
CCTATACTTAGGAAAAAGTTTTTCAGGAACAAATCTTGAAATAGAAAGGGTTTTTGGTAAACCTGATAAATCCTACAAGAATGAATTCCCTAGTAACAGGATTATATTTTACAGCTTTTAT
Junction sequence
ATAAAAGCTGTAAAATATAATTTTTACTATTGCTGATCAAATATTACAATATG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Akagi, K., et al.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res ,2014,24(2): 185-199.
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