EYA2 _CESC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004640
Fusion event
HPV-EYA2 integration
Validated
Yes
Detection method
FISH, WGS, RNA-seq, qPCR
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
24201445
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Gene
E1
Start
1685
End
1703
Integrated sequence
GTGTTACTATTAGTAAGAT
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
45660938/47032273 (Hg38)
End
45660912/47032299 (Hg38)
Location type
Intronic
Target gene
EYA2
miRNAs that regulate target gene
hsa-mir-30a-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/1327093; hsa-mir-1-1/Downstream/134668;
Nearest TSS
ENST00000382410/Upstream/30813; ENST00000475856/Downstream/56940;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/136892, chr20-CpG: 38/Downstream/206611
Target sequence
GAACATGCAGGGAATTCCTGATTTTT
Junction sequence
AAAAATCAGGAATTCCCTGCATGTTCCTACATGTGTTACTATTAGTAAGAaactacatataaaaatacta
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Akagi, K., et al.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res ,2014,24(2): 185-199.
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