Basic Information
VIS ID
TVIS20004643
Fusion event
HPV-LINC01605 integration
Validated
Yes
Detection method
FISH, WGS, RNA-seq, qPCR
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
24201445
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Gene
E7
Start
552
End
580
Integrated sequence
GCTGTAATCATGCATGGAGATACACCTAC
Host Sequence
Chromosome
chr8
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
37346181/37488663 (Hg38)
End
37346204/37488686 (Hg38)
Location type
Intronic
Target gene
LINC01605
Nearest miRNA
hsa-mir-124-1/Upstream/7531315; hsa-mir-10400/Downstream/3782362;
Nearest TSS
ENST00000518652/Upstream/8574; ENST00000522643/Downstream/5148;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/2252070, chr8-CpG: 351/Downstream/205740
Downstream sequence
AAACTCGCCACCATTATTTTCCTT
Target sequence
AACTCGCCACCATTATTTTCCTT
Junction sequence
AGCTGTAATCATGCATGGAGATACACCTAAACTCGCCACCATTATTTTCCTT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Akagi, K., et al.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res ,2014,24(2): 185-199.
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