Basic Information
VIS ID
TVIS20004658
Fusion event
HPV-ACTL7B integration
Validated
No
Detection method
RNA-Seq
Data source
download(HPVbase)
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23740984
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Not given
Gene
E2
Start
2769
Host Sequence
Chromosome
chr9
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
111541176/108778896 (Hg38)
End
111541176/108778896 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA9E
Target gene
ACTL7B
Nearest miRNA
hsa-let-7a-1/Upstream/2177874; hsa-mir-12126/Downstream/267333;
Nearest TSS
ENST00000422679/Upstream/75804; ENST00000333999/Downstream/78071;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1061757, chr9-CpG: 67/Downstream/76144
Upstream sequence
TCCTTGTATTCTTCTTTTATTCTTGTCTTGACAAACTGTTCAAATATCTTAAAACACAGACACAGAAGAAAAACATCTGACATTTTGGTATCTTTCATCT
Downstream sequence
cacacacttgttaaaatcaattcatcagcacctcccagacctcttgaatcagtctctgaattgaatctcaaaggcctaccttttaataagGCGTAGCATA
Reference
Khoury, J. D., et al. Landscape of DNA virus associations across human malignant cancers: analysis of 3,775 cases using RNA-Seq. J Virol,2013, 87(16): 8916-8926.
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