hsa-mir-21-5p _CESC.png
KLF5 _CESC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20004683
Fusion event
HPV-KLF5 integration
Validated
No
Detection method
RNA-Seq
Data source
download(HPVbase)
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23740984
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Not given
Gene
E6
Start
447
Host Sequence
Chromosome
chr13
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
73620072/73045934 (Hg38)
End
73620072/73045934 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA13B
Target gene
KLF5
miRNAs that regulate target gene
hsa-mir-145-5p ; hsa-mir-141-3p ; hsa-mir-9-5p ; hsa-mir-128-3p ; hsa-mir-21-5p ; hsa-mir-143-3p ; hsa-mir-4480 ; hsa-mir-489-3p ; hsa-mir-4668-3p ; hsa-mir-153-3p
Nearest miRNA
hsa-mir-1297/Upstream/6827610; hsa-mir-1267/Downstream/4652078;
Nearest TSS
ENST00000623511/Upstream/76295; ENST00000476859/Downstream/9042;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/263460, chr13-CpG: 163/Downstream/12788
Nearest cancer related gene
KLF5(OG, No orient, 0)
Upstream sequence
TCCTACAGTTAGACTTCTATCAAAGGGTCATTGTGCCAACTGGAATTCTTTCCAATTCGAGAAATAAGAATTTGAGGAATCTCTAAGGGTAGAAATGACT
Downstream sequence
TCTATcgggagacagcacactaacgcaagagggccaatggggttctgccacctgtatttgtaaataaaatttcactggtacacagccatgcctgttcact
Reference
Khoury, J. D., et al. Landscape of DNA virus associations across human malignant cancers: analysis of 3,775 cases using RNA-Seq. J Virol,2013, 87(16): 8916-8926.
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