EPSTI1 _HNSC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20005046
Fusion event
HPV-EPSTI1 integration
Validated
No
Detection method
WGS, RNA-seq, Whole-Exome sequencing, PCR
Data source
Curated
Sample type
Tumor
Disease
Head and neck squamous cell carcinoma (HNSCC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
25313082
Virus Sequence
Virus name
HPV
Subtype
HPV33
Reference genome
Not given
Gene
E2
Start
3623
Host Sequence
Chromosome
chr13
Cytoband
q14.11
Reference genome
GRCh37/hg19
Start
43504600/42930464 (Hg38)
End
43504600/42930464 (Hg38)
Location type
Intronic
Target gene
EPSTI1
miRNAs that regulate target gene
hsa-mir-146a-5p ; hsa-mir-654-5p
Nearest miRNA
hsa-mir-2276/Upstream/1362069; hsa-mir-1267/Downstream/1265665;
Nearest TSS
ENST00000623511/Upstream/87577; ENST00000474320/Downstream/33119;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/657793, chr13-CpG: 38/Downstream/61474
Junction sequence
ACATAACTGGGTATGAGCAAATGACATTCACACACCTATAAGCACTCACAGAGC---CTGTATCTTAAACATTTTAAACTATTTGATTCACCTTTTAAATGCAC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Parfenov, M., et al. Characterization of HPV and host genome interactions in primary head and neck cancers. Proc Natl Acad Sci U S A,2014,111(43): 15544-15549.
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