Basic Information
VIS ID
TVIS20005051
Fusion event
HPV-ASIC2 integration
Validated
No
Detection method
WGS, RNA-seq, Whole-Exome sequencing, PCR
Data source
Curated
Sample type
Tumor
Disease
Head and neck squamous cell carcinoma (HNSCC)
Quality evaluation
Perfect
Reported year
2014
PubMed ID
25313082
Virus Sequence
Virus name
HPV
Subtype
HPV33
Reference genome
Not given
Gene
E1
Start
995
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
GRCh37/hg19
Start
32128924/33801905 (Hg38)
End
32128924/33801905 (Hg38)
Location type
Intronic
Target gene
ASIC2
Nearest miRNA
hsa-mir-1180/Upstream/1451703; hsa-mir-10226/Downstream/3231840;
Nearest TSS
ENST00000595228/Upstream/113102; ENST00000582685/Downstream/14856;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/508458, chr17-CpG: 46/Downstream/238019
Junction sequence
TTAGTAGACGTACGGGGGATCCAGTGTCAGAGGACGAAAATGAAGATGACTGTGACAG---AGTGTAGTTGGCTAGAACTGGACGAGAGGGAGGTATGGACCAC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Parfenov, M., et al. Characterization of HPV and host genome interactions in primary head and neck cancers. Proc Natl Acad Sci U S A,2014,111(43): 15544-15549.
Curate