VISDB Viral Integration Site DataBase

VIS ID

TVIS20005056

Fusion event

HPV-chr17:q23.1 integration

Validated

Yes

Detection method

RNA-Seq+RT-PCR

Data source

Curated

Sample type

Disease

Adenocarcinoma (AC)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HPV

Subtype

HPV18

Reference genome

Not given

Chromosome

chr17

Cytoband

q23.1

Reference genome

Start

End

58007502/59930141 (Hg38)

Location type

Intronic

Target gene

RPS6KB1 ; TUBD1

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-103a-3p ; hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-877-3p ; hsa-mir-877-5p ; hsa-mir-15a-5p ; hsa-mir-107 ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-548c-3p ; hsa-mir-4668-3p ; hsa-mir-5571-3p ; hsa-mir-6838-5p ; hsa-mir-1253 ; hsa-mir-3161 ; hsa-mir-145-5p ; hsa-mir-1276 ; hsa-mir-138-2-3p ; hsa-mir-451b ; hsa-mir-599 ; hsa-mir-580-3p ; hsa-mir-6770-5p ; hsa-mir-500b-5p ; hsa-mir-362-5p ; hsa-mir-500a-5p ; hsa-mir-376a-2-5p ; hsa-mir-7150 ; hsa-mir-4451 ; hsa-mir-4650-3p ; hsa-mir-5681a ; hsa-mir-3529-5p ; hsa-mir-379-5p ; hsa-mir-96-5p ; hsa-mir-182-5p ; hsa-mir-1271-5p ; hsa-mir-2054 ; hsa-mir-190a-3p ; hsa-mir-380-3p ; hsa-mir-411-3p ; hsa-mir-379-3p ; hsa-mir-4495 ; hsa-mir-5011-5p ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-4284 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-2276-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-1281 ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-660-3p ; hsa-mir-4485-5p ; hsa-mir-6890-3p ; hsa-mir-598-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-6720-3p ; hsa-mir-6778-3p ; hsa-mir-4258 ; hsa-mir-4740-3p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-4438 ; hsa-mir-620 ; hsa-mir-4531 ; hsa-mir-1270 ; hsa-mir-550a-3p ; hsa-mir-200c-5p ; hsa-mir-6879-3p ; hsa-mir-139-3p ; hsa-mir-4524a-3p ; hsa-mir-550b-3p ; hsa-mir-215-3p ; hsa-mir-6773-3p ; hsa-mir-3664-5p ; hsa-mir-514a-5p ; hsa-mir-4714-5p ; hsa-mir-455-5p ; hsa-mir-200c-3p ; hsa-mir-218-5p ; hsa-mir-1271-3p ; hsa-mir-4275 ; hsa-mir-550a-3-5p ; hsa-mir-550a-5p ; hsa-mir-550b-2-5p ; hsa-mir-122-5p ; hsa-mir-143-5p ; hsa-mir-3135b ; hsa-mir-3652 ; hsa-mir-4430 ; hsa-mir-4634 ; hsa-mir-504-3p ; hsa-mir-5693 ; hsa-mir-5698 ; hsa-mir-6499-3p

Nearest miRNA

hsa-mir-10226/Upstream/182; hsa-mir-1250/Downstream/112884;

Nearest TSS

Nearest CpG islands

chr17-CpG: 73/Target, None/Upstream, None/Downstream

Nearby gene

VMP1 ; RNFT1(+) ;

Upstream sequence

TTCTGCGTGTTAGATCCCAGGGATGCTGGCTTTGTCAGTCTTCACAGGTGTTGCCGGTGACTATCCACCAAGGTGGCCCTAAGGGGCTGTTGTAGTTCCA

Downstream sequence

AAGAGAGGGAATATTTATGGAAGACACTGCCTGGTAAGTGAACTTTTTGTGGTTGCATAGATTCAGGTAATTACAAGCAAAGCCCCATTCCCACTATGGG

Target sequence

gcccaggctggactgctgcagtggcgcgatcttggctcactgcaagctccgcctcacgggttcacgccattctcctgcctcagcctcccgagcagctgggactacaggcgcccaccaccacacctggctaattttttatatttttagtagaggcggtgtttcaccatgttagccaggatggtcttgatctcctgacctcgtgatctgcctgcctcggcctcccaaagtgctgggattacaggcatgagccaccgt